Natural Hormone Education and Research Library
Your source for natural hormone or bioidentical hormone information and how to have hormone balance, the Library includes dozens of articles by natural progesterone pioneer John R. Lee, M.D. and his co-author Virginia Hopkins about how to use natural hormones, especially natural progesterone cream, to treat hormone imbalances. Here's where you'll find answers to all your natural hormone questions and expert guidance on how to create a natural hormone program that's right for you. Whether you need natural hormones for menopause, perimenopause or even PMS, you'll find hormone balance answers here.Breast Cancer News and Reviews
Here's where to find news about breast cancer research, and reviews of breast cancer studies by Dr. John Lee and Virginia Hopkins
Cortisol and the Stress Connection
In this article originally published in the John R. Lee, M.D. Medical Letter, Dr. John Lee and Virginia Hopkins explain how the adrenal hormone cortisol work in the body, and how too much or too little can affect your health.
Cortisol Levels, Thyroid Function and Aging
A fascinating interview from the John R. Lee, M.D. Medical Letter with Dr. David Zava, about how cortisol levels affect thyroid function and aging.
Dietary Guidelines for Osteoporosis
Osteoporosis is a multi-faceted problem and not just a calcium deficiency disease. Dr. john Lee explains how a bone building diet and overall good nutrition can make all the difference in keeping bones strong.
Dr. John Lee Comments on a Progesterone Study
Dr. John Lee comments on Dr. Helene Leonetti's progesterone research.
Dr. John Lee's 3 Rules for HRT
A Dr. John Lee classic - clear, commonsense guidelines for when and how to use bioidentical hormone replacement therapy (BHRT), also called natural hormone replacement therapy (NHRT).
Environmental Illness
A fascinating and informative interview from the John R. Lee, M.D. Medical Letter with William J. Rea, M.D., a pioneer and the leading researcher and clinician in the field of environmental medicine and chemical sensitivity, which is the treatment of illness caused by food and environmental factors as wide-ranging as such as pesticides, air and water pollution, solvents and formaldehyde, gas stoves, fragrances, and electromagnetic fields.
Progesterone Cream FAQs
Dr. John Lee and Virginia Hopkins answer frequently asked questions about natural progesterone cream include: what is natural progesterone; how to use natural progesterone cream; what dosage to use; real progesterone vs. progestins; how safe is progesterone, and when to use progesterone cream.
Fibroids and Natural Progesterone
Insights from Dr. John Lee about two of the most common problems women have after 30, fibroids and uterine enlargement and how this relates to progesterone and estrogen dominance.
Fibroid Q&A with Dr. John Lee
Dr. John Lee answers a question about fibroids from a woman nearing menopause.
Gallbladder Disease and Hormones
Women are twice as likely as men to develop gallstones, probably largely due to unidentified estrogen dominance and the excessive estrogen used in hormone replacement therapy (HRT).
How to Get Off HRT
Questions and Answers from Dr. Lee and Virginia Hopkins about how to get off HRT and onto natural hormones, also known as bioidentical hormone therapy (BHRT). How to have balanced hormones, and relief from menopausal symptoms, without using conventional HRT.
Hormone Balance and Nutrition
A few tips from Dr. John Lee and Virginia Hopkins about how nutrition can affect your hormone balance.
How to Prevent Osteoporosis
Dr. John Lee and Virginia Hopkins give women helpful information on how to prevent osteoporosis by giving information on what to avoid as well as lifestyle tips.
How to Interpret Your Saliva Hormone Test
Dr. John Lee explains how to read a saliva hormone test.
How to Sleep Better
Many menopausal women have trouble sleeping, also called insomnia, but this article on how to sleep better by Dr. John Lee will help everyone get a better night's sleep.
How to Treat Fibroids Naturally
An interview with Carolyn DeMarco, M.D. on natural treatment for fibroids and heavy bleeding.
HRT and Osteoporosis
Dr. John Lee and Virginia Hopkins explain why progesterone is as least as important as estrogen when it comes to building and maintaining bone density in women around the time of menopause.
HRT, Breast Cancer and the Women's Health Initiative
An article by Dr. John Lee about why the risks of conventional HRT outweigh the benefits, and how major research, including the Women's Health Inititive (WHI) and the Million Women Study have finally made that clear.
Infertility: Getting Pregnant and Staying Pregnant
Dr. John Lee shares stories from his practice about helping women get pregnant and explains what causes infertility, how fertility works and how to prevent a miscarriage.
Insomnia and Hormones
Some types of hormone imbalance can contribute to sleepless nights. Find out what might be causing your tossing and turning.
Intro: What Your Dr May Not Tell You About Breast Cancer
Here's where you can read the introduction to Dr. John Lee's informative and useful book, "What Your Doctor May Not Tell You about Breast Cancer."
Is DCA a Cure for Cancer?
News about a chemical called dichloroacetic acid (DCA), an inexpensive drug that may cure cancer without side effects, is making the rounds of cyber space at warp speed.
Men's Hormones by Dr. John Lee
Testosterone deficiency in middle-aged men is often called male menopause or andropause. Dr. John Lee discusses what hormone imbalance means in males and how to supplement with testosterone.
Menopause Book Chapter 1
Here's where you can read chapter one of Dr. John Lee and Virginia Hopkins' best-selling book, What Your Doctor May Not Tell You About Menopause.
Natural Progesterone - What Women Say
What women say about how natural progesterone has helped them restore hormone balance and combat estrogen dominance, plus what natural progesterone is and its effects in the body.
Dr. Christiane Northrup Shares Her Wisdom of Menopause with Oprah
Who better to give Oprah menopause advice than Dr. Christiane Northrup, one of the pioneers in the use of natural hormones, and an articulate, thoughtful voice for making the menopausal transition with awareness.
Your Ovaries and PCOS with Dr. Jerilyn Prior
An interview with Jerilyn Prior, M.D., one of the top researchers on the subject of women's hormones, and ovulation and PCOS in particular.
PMS and Hormones
Dr. John Lee and Virginia Hopkins explain why premenstrual syndrome (PMS) is the most common health complaint of premenopausal women. While there are no magic bullets, hormone balance and progesterone in particular can help PMS, and why estrogen dominance is related to PMS.
PMS and Stress
Stress can be a direct cause of premenstrual syndrome (PMS), and it can certainly make it worse. Stress creates high cortisol levels, which creates hormone imbalances. Excerpted from What Your Doctor May Not Tell You about PREmenopause by Dr. John Lee and Virginia Hopkins.
PMS and the Stress Connection
Stress can be a direct cause of premenstrual syndrome (PMS), and it can certainly make it worse. Stress creates high cortisol levels, which creates hormone imbalances. Excerpted from What Your Doctor May Not Tell You about PREmenopause by Dr. John Lee and Virginia Hopkins.
Postpartum Depression, Stress and Nutrition
An article by Dr. Dean Raffelock about how stress and poor nutrition can contribute to postpartum depression.
Premenopause Book Chapter 1
Excerpts from Chapter One of What Your Doctor May Not Tell You About PREmenopause, by John R. Lee, M.D. and Virginia Hopkins, including why you might recognize your hormone imbalance symptoms in this book if you're between the ages of thirty and fifty, and why you can look forward to perimenopause and menopause.
Premenstrual Syndrome (PMS)
No it's not all in your head! Here's where to find articles about PMS by Dr. John Lee and Virginia Hopkins.
Progesterone and Estrogen Effects
Progesterone and estrogen balance each other in the body. Here is a list of estrogen's effects on the body, and the complementary effects of progesterone. Both hormones have important effects throughout the body.
Progesterone and Osteoporosis
Dr. John Lee explains that osteoporosis diagnosis usually comes around the time of menopause, when hormones are often imbalance, and how both progesterone and estrogen can help maintain healthy bones.
Mammograms - Should We or Shouldn't We?
Dr. John Lee makes a strong case that routine mammograms don't save lives and may be more harmful than helpful.
Saliva Test FAQs
Here's practical information about the process of ordering your saliva test, what to do when you receive it, how to return it, and how to read the results.
Saliva Test Q & As
Questions from women about saliva testing, answers from Dr. John Lee and Virginia Hopkins.
Saliva Tests vs. Blood Tests by Dr. John Lee
Dr. John Lee explains why it's so important to use saliva testing vs. serum blood testing when trying to determine the cause of a hormone imbalance.
Scientific References about Natural Hormones
Scientific references for many of the articles on this website, including progesterone, estrogen and heart disease, bone density, HRT, saliva testing, breast cancer and much more.
Soy and Hormone Balance
Is soy really a health food, or does it have too many antinutrients to qualify? And does it really help menopause symptoms? Dr. John Lee and Virginia Hopkins weigh in on whether soy is really the health food it is advertised to be and whether it helps menopause symptoms.
Soy Foods and Menopause
Soy is widely touted as a cure-all for menopausal symptoms, but does it really work, and do you really want to eat that much soy?
Symptoms of Estrogen Dominance
Estrogen dominance is a term coined by Dr. Lee, and this is his famous (and much copied) list of the symptoms and conditions associated with estrogen dominance.
The Biochemistry of Saliva Testing
If you're a health professional or a science geek, you'll appreciate this article by Dr. John Lee on the biochemistry and physiology of saliva hormone testing, complete with references.
Use Caution with Soy Foods
Soy foods have become wildly popular in the U.S. as a health food, but Dr. John Lee explains why it's wise to eat soybeans in moderation and consider how the Japanese eat soy, which is to say almost always fermented, as in miso and tempeh, and eaten with fish and seaweed to offset the antinutrients found in soybeans.
Vitamin D Nutrient Review
Vitamin D is an essential vitamin and an essential hormone.
What Your Doctor May Not Tell You about Heartburn
You don't need to take expensive drugs every day to avoid heartburn. Here are some of Dr. John Lee's commonsense solutions for reflux and heartburn.
What Your Dr May Not Tell You About Breast Cancer: Chapter 1
Here's where you can read the controversial Chapter 1 of John R. Lee M.D.'s courageous book, "What Your Doctor May Not Tell You About Breast Cancer," and the politics of tamoxifen, mammograms, chemotherapy and more.
What Your Dr May Not Tell You About Iron and Anemia
Iron is an essential mineral, but too much or the wrong kind can be harmful. Find out which are the best foods to increase iron, how and when to test for iron, and how to determine the underlying cause of the deficiency if you have anemia.
What Your Dr. May Not Tell You About Stress
If you think stress might be affecting your health, you'll want to read this article about how tired adrenal glands can cause poor health and hormone imbalances.
What Your Dr. May Not Tell You About Your Thyroid
Millions of people have low thyroid and take supplements such as synthroid for it. This article by Dr. John Lee and Virginia Hopkins will explain how to tell if you have low thyroid, list the symptoms of low thyroid, how to supplement for low thyroid, and how to test for low thyroid.
What Your Dr. May Not Tell You About Cholesterol
Are cholesterol numbers really meaningful, or are we being sold a bill of goods by the pharmaceutical industry? This article by Dr. John Lee and Virginia Hopkins explains how cholesterol really works.
What Your Dr. May Not Tell You about PCOS
A detailed article about PCOS by Dr. John Lee and Virginia Hopkins, gives women detailed answers to their questions about causes and treatment, including info on hormones, diet and exercise.
Why Breast Cancer Rates Dropped
Breast cancer rates dropped dramatically in 2002 and 2003 after years of rising. Why the drop and how can we maintain this trend?
Why We Like Saliva Testing
Saliva testing is fairly new to conventional medicine, so there is confusion and misunderstanding about it. This article by Dr. John Lee, Dr. David Zava and Virginia Hopkins will explain why saliva hormone testing is so important and gives the basics on how it works.
Xenohormones and Your Environment
We are awash in a sea of xenohormones but with education and awareness you can avoid many of them. Find out how in this article by Dr. John Lee and Virginia Hopkins.
Xenohormones and Your Health
Xenohormones are chemical hormone imposters that can cause hormone imbalance and cancer. Read this informative article by Dr. John Lee and Virginia Hopkins.
Estriol - the Safe Estrogen Hormone
Estriol is a safe estrogen hormone that has been used for decades in Europe to treat hot flashes and vaginal dryness.
Estrogen Advice from Dr. John Lee
Dr. John Lee gives straight answers to what women want to know about estrogen, including what kind of estrogen to take and how much.
Introduction to Dr. John Lee
Dr. John Lee was a pioneer in the field of natural hormones, also called bioidentical hormones. Here's where to find out more about Dr. John Lee and the history of his revolutionary discoveries about natural hormones, and in particular, progesterone cream.
Articles by Dr. John Lee
Dr. John Lee and Virginia Hopkins co-wrote hundreds of articles, most of them originally published in the John R. Lee, M.D. Medical Letter. Those available on this website are listed here.
Hormone Balance for Men - A Booklet by John R. Lee, M.D.
Men also suffer from hormone imbalances, especially as they pass middle age or if they are overweight.
Saliva Test Kits
Saliva testing for hormones is easy, accurate and gives the most useful information about your hormone levels. You can "spit" at home and mail it to the lab in a prepaid package. Here's where to find saliva hormone test kits for estrogen, progesterone, testosterone, DHEA, cortisol and more.
SALE!! Videos Featuring Dr. John Lee and Dr. David Zava
The next best thing to being there! Listen and watch as Dr. John R. Lee and Dr. David Zava teach us about natural hormones and hormone balance.



